Xi's trip underlines the importance Beijing places on ties with Russia and Central Asia as the ruling Communist Party promotes its strategic ambitions amid tension with Washington, Japan and India.
Wearing a blue suit, Xi was met on the airport tarmac by President Kassym-Jomart Tokayev and an honour guard, all of whom wore masks.
Tokayev's government said the two leaders would discuss energy markets and global economic turmoil. Kazakhstan, a sparsely populated country of 19.4 million people and sprawling grasslands, is a major oil and gas producer. China is a leading customer.
On Thursday, Xi is due to fly to Samarkand in neighbouring Uzbekistan for a summit of the eight-nation Shanghai Cooperation Organisation, led by China and Russia.
Beijing and Moscow see the SCO as a counterweight to US alliances in East Asia.
Other SCO governments include India, Kazakhstan, Kyrgyzstan, Pakistan and Tajikistan. Observers include Iran and Afghanistan.
The Chinese leader is promoting a "Global Security Initiative" announced in April following the formation of the Quad by Washington, Japan, Australia and India in response to Beijing's more assertive foreign policy.
Xi has given few details, but US officials complain it echoes Russian arguments in support of Moscow's attack on Ukraine.
Xi and Putin plan to hold a one-on-one meeting and discuss Ukraine, according to the Russian president's foreign policy adviser Yuri Ushakov.