The decision comes a day after rival BP abandoned its stake in Russian oil giant Rosneft in a move that could cost the British company more than $US25 billion ($A35 billion).
Norway's Equinor also plans to exit Russia.
Shell said in a statement it will quit the flagship Sakhalin 2 LNG plant in which it holds a 27.5 per cent stake, and which is 50 per cent owned and operated by Russian gas giant Gazprom.
Shell said the decision to exit Russian joint ventures will lead to impairments. Shell had around $US3 billion ($A4.2 billion) in non-current assets in these ventures in Russia at the end of 2021, it said.
"We are shocked by the loss of life in Ukraine, which we deplore, resulting from a senseless act of military aggression which threatens European security," Shell Chief Executive Ben van Beurden said in a statement.
"Shell have made the right call to divest from Russia," Britain's Business Secretary Kwasi Kwarteng said on Twitter.
The Sakhalin 2 project, located off Russia's northeastern coast, is huge, producing around 11.5 million tonnes of LNG per year, which is exported to major markets including China and Japan.
For Shell, the world's largest LNG trader, leaving the project deals a blow to its plans to supply gas to fast-growing markets in the coming decades.
Shell said the Russia exit will not affect its plans to switch to low-carbon and renewable energy.
The company also plans to end its involvement in the Nord Stream 2 Baltic gas pipeline linking Russia to Germany, which it helped finance as part of a consortium of companies. Germany last week halted the project.
Shell will also exit the Salym Petroleum Development, another joint venture with Gazprom.
Together, Salym and Sakhalin 2 contributed $US700 million ($A969 million) to Shell's net earnings in 2021.
Norway's Equinor, majority owned by the Norwegian state, said earlier on Monday it would start divesting from its joint ventures in Russia.
That came after the country's sovereign wealth fund, the world's largest, said on Sunday it would divest its Russian assets.
Other Western companies including global bank HSBC and the world's biggest aircraft leasing firm AerCap said they plan to exit Russia as Western governments ratchet up economic sanctions on Moscow.
