The onetime Republican vice presidential candidate and ex-governor of Alaska gets another chance to prove to a federal jury that the newspaper defamed her with the 2017 editorial falsely linking her campaign rhetoric to a mass shooting. Palin said it damaged her reputation and career.
The Times has acknowledged the editorial was inaccurate but said it quickly corrected an "honest mistake".
The trial, expected to last a week, comes after the 2nd US Circuit Court of Appeals restored the case last year. Jury selection is scheduled to begin on Monday morning.
In February 2022, Judge Jed S Rakoff in Manhattan rejected Palin's claims in a ruling issued while a jury deliberated. The judge then let jurors deliver their verdict, which went against Palin.
In restoring the lawsuit, the 2nd Circuit said Rakoff's dismissal ruling improperly intruded on the jury's work.
It also cited flaws in the trial, saying there was erroneous exclusion of evidence, an inaccurate jury instruction and an erroneous response to a question from the jury.
The retrial occurs as President Donald Trump and others in agreement with his views of news coverage have been aggressive toward media outlets when they believe there has been unjust treatment.
Trump sued CBS News for $US20 billion ($A32 billion) over the editing of a 60 Minutes interview with his 2024 opponent, former Vice President Kamala Harris, and also sued the Des Moines Register over an Iowa election poll that turned out to be inaccurate.
ABC News settled a lawsuit with Trump over its incorrect claim the president had been found civilly liable for raping writer E Jean Carroll.
Kenneth G Turkel, a lawyer for Palin, did not return a request for comment.
Charlie Stadtlander, a spokesperson for the Times, said Palin's claim stemmed from "a passing reference to an event in an editorial that was not about Sarah Palin".
"That reference was an unintended error, and quickly corrected. We're confident we will prevail and intend to vigorously defend the case," Stadtlander said in a statement.
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