The Israeli military conducted an arrest raid before dawn on Tuesday in the town of Zababdeh south of Jenin, local medics said.
The Palestinian Health Ministry reported that 17-year-old Othman Abu Kharj was fatally shot in the head.
The raid came as Israeli security forces were still searching for the Palestinian gunman who carried out a shooting in the northern Palestinian city of Hawara that killed an Israeli father and son on Saturday.
The Israeli military said its forces arrested 15 Palestinian suspects in several northern West Bank towns. In Zababdeh, Israeli security forces said they opened fire at residents who threw explosive devices at them.
In the southern West Bank, the Israeli army captured two Palestinians who were suspected in a shooting the day before that killed an Israeli woman and seriously wounded a man.
The Israeli military said the two suspects confessed during interrogation to involvement in the attack near the Palestinian city of Hebron.
Israeli security forces said they also confiscated the rifle used to shoot at the car on Monday.
Palestinian media identified the two suspects arrested near Hebron as Saqer and Muhamad al-Shantir.
The Israeli military said its forces further conducted large-scale searches and arrest raids throughout the West Bank, interrogating 20 Palestinians, confiscating illegal vehicles and arresting an additional 13 suspects near Hebron.
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