Earlier in the week, Harris was in Georgia, where she helped distribute meals, toured the damage and consoled families hard-hit by the storm.
President Joe Biden, too, visited the disaster zone.
During stops over two days in the Carolinas, Florida and Georgia, Biden surveyed the damage and met with farmers whose crops have been destroyed.
The two have been vocal and visible about the government's willingness to help, and the administration's efforts so far include covering costs for all of the rescue and recovery efforts across the southeast for several months as states struggle under the weight of the mass damage.
President Joe Biden visited the in the Carolinas, Florida and Georgia to survey Helene's damage. (AP PHOTO)
In a letter to congressional leaders, Biden wrote that while the Federal Emergency Management Agency's Disaster Relief Fund "has the resources it requires right now to meet immediate needs, the fund does face a shortfall at the end of the year".
More than 200 people have died. It's the worst storm to hit the US mainland since Katrina in 2005, and scientists have warned such storms will only worsen in the face of climate change.
But in this overheated election year, even natural disasters have become deeply politicised as the candidates crisscross the disaster area and in some cases visit the same venues to win over voters in battleground states.
Trump has falsely claimed the Biden administration is not doing enough to help affected people in Republican areas and has harshly criticised the response.
He has, in Helene's aftermath, espoused falsehoods about climate change, calling it "one of the great scams of all time".
During a stop in Fayetteville, North Carolina on Thursday, Trump renewed his complaints about the federal response and cited "lousy treatment to North Carolina in particular".
In fact, the state's Democratic governor, Roy Cooper, said this week the state has already seen more than 50,000 people be registered for FEMA assistance, and about $US6 million ($A8.8 million) has been paid out.
Donald Trump has made false claims about the Biden administration's response to Hurricane Helene. (AP PHOTO)
Biden, meanwhile, has suggested the Republican House speaker is withholding critical disaster funding.
Harris's visits, meanwhile, present an additional political test in the midst of a humanitarian crisis.
She is trying to step into a role for which Biden is well known - showing the empathy that Americans expect in times of tragedy - in the closing stretch of her White House campaign.
Harris said this week that she wanted to "personally take a look at the devastation, which is extraordinary".
She expressed admiration for how "people are coming together. People are helping perfect strangers."
She said that showed "the vast majority of us have so much more in common than what separates us", an echo of a line she frequently uses on the campaign trail.
"We are here for the long haul," she said.
