The airport on Monday confirmed on X that an "incident" occurred with the Delta flight from the US city of Minneapolis and that all passengers and crew were accounted for.
One passenger was critically injured and seven others were also hurt, paramedics said.
Video from the scene showed the plane upside down on the snowy tarmac as emergency workers hose it down.
The plane was somewhat obscured by snow from a winter storm that hit Toronto at the weekend.
"Emergency teams are responding," the airport said in a post on the social platform X.
"All passengers and crew are accounted for."
Delta said it was "aware of reports of Endeavor Flight 4819 operating from Minneapolis-St Paul to Toronto-Pearson International Airport as involved in an incident."
Ontario's Premier Doug Ford said on X he was "relieved there are no casualties after the incident at Toronto Pearson".
"Provincial officials are in contact with the airport and local authorities and will provide any help that's needed," Ford said.
Toronto is the capital of Ontario's province.
It is at least the fourth major aviation mishap in North America in the past month.
A commercial jetliner and an Army helicopter collided near the nation's capital on January 29, killing 67 people.
A medical transportation plane crashed in Philadelphia on January 31, killing the six people on board and another person on the ground and 10 were killed in a plane crash in Alaska.
15°C