Pakistan is grappling with a surge in strikes by separatist ethnic militants in the south and Islamist militants in its northwest.
Balochistan Inspector General of Police Mouzzam Jah Ansari said at least 24 people had been killed, with many of the injured in a critical condition.
Investigators are probing the scene of a deadly blast at a train station in southwest Pakistan. (AP PHOTO)
"The target was army personnel from the Infantry School," he said.
Civil hospital spokesman Dr Wasim Baig said the hospital was treating 44 people injured in the blast.
Police Senior Superintendent Muhammad Baloch said the blast was believed to have been a suicide bomb.
"The blast took place inside the railway station when the Peshawar-bound express was about to leave for its destination," Baloch said.
No group has claimed responsibility for the blast.
In August, at least 73 people were killed in Balochistan province after separatist militants attacked police stations, railway lines and highways.
The assaults in August were the most widespread in years by militants fighting a decades-long insurgency to win secession of the resource-rich southwest province, home to major China-led projects such as a port and a gold and copper mine.Â
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