The Saints won 51-32, with Rebecca Ware scoring 32 goals and Laura Gorman 19.
Katamatite and Jerilderie kept their unbeaten starts to the season going with wins over Yarroweyah and Katandra.
The Tigers defeated Yarroweyah 54-24 and Jerilderie saluted 44-27 against Katandra.
Tocumwal defeated Mathoura by 13, winning 45-32, recording its third win of the season.
Coach Kate Bird was happy with the performance despite her side being far from its best.
“We are definitely not at our best, we are starting to gel, but we have a long way to go,” Bird said.
“It was a really good win coming off the win against Strathy.”
Bird praised the work of her shooters and debutant Macey White.
“Macey, who's only 15, made her debut in the second half and did really well,” she said.
“The shooting accuracy of our goalers (also stood out).
“It makes a huge difference when they are doing their jobs well."
Picola United won 42-30 against Rennie, taking its second win of the season and Strathmerton knocked off Tungamah 58-43.
Deniliquin Rovers had the bye.
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