The 36-year-old woman was last seen leaving a Brunswick supermarket on April 10, 2021, after telling family she was going to visit a friend in Brighton.
Ms Hamka's former boyfriend Toby Loughnane has been charged with her murder and faced Melbourne Magistrates Court by videolink on Monday.
Oscar Newman appeared in person over charges alleging he assisted in the murder.
The court heard on the last day she was seen, Ms Hamka sent her friend Shane Allen a text message saying "sorry I blew out".
He said he called her at 3am or 4am on April 11 after seeing the text.
"She didn't sound right. I was just checking, worried about her," he told the court.
Under questioning by Loughnane's barrister Daniel Sala, he said the phrase "blew out" was used by people who had taken too much of the drug GHB.
Another witness said Ms Hamka and Loughnane argued in front of her for more than three hours in the weeks before she went missing.
The witness, a friend of Loughnane, had not seen Ms Hamka for eight years and did not know the pair were in a relationship.
She told the court she went to Loughnane's Brighton home on February 20 last year after she was contacted by him on Facebook.
She said Loughnane and Ms Hamka had an altercation "for hours" between 1am and 4.30am, and she stayed at the house during their dispute.
"Toby was my friend, and seeing Maryam go through what she went through that night, I stayed because to be honest I was in fear," she said.
"I was trying to get a Didi home, an Uber home, and I couldn't get any cars."
Ms Hamka's body has never been found.
The committal hearing will continue on Tuesday.
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