West Australian fire authorities issued the emergency warning on Saturday afternoon at 12.52pm, Perth time.
The evacuation orders are in place for residents in an area bounded by Gemma Road to the north, Rockingham Road to the east, Dooley Street to the south and the coast to the west in parts of Henderson, Hope Valley, Naval Base and Wattleup in the Kwinana and Cockburn council areas.
Residents are being told they must act immediately to survive.
The bushfire started in grassland at the intersection of Rockingham Road and Lussky Road in Hope Valley.
If the way is clear, residents must leave now for a safer place and must not wait, the Department of Fire and Emergency Services (DFES) said.
Residents who cannot leave must take shelter in their home in a room away from the fire front and with access to two exits and water.
All doors and windows should be shut. Evaporative air conditioners should be off but water should continue to run through the system.
A watch and act warning is in place for residents further north, in an area bounded by Gemma Road to the south, Rockingham Road to the east, Nautical Road to the north and the coast to the west in parts of Henderson and Wattleup.
This means people who have a plan to leave or are unprepared should leave now.
DFES said those who plan to defend their homes should make final preparations to do so but mains water could not be relied upon and independent water supplies should be used.
Residents from the affected areas who are not at home have been advised not to return.
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