The 28-year-old was in strikingly good form again in Saturday morning's third round, crushing doubles world No.1 Katerina Siniakova without dropping a game before the ailing Czech pulled out with injury after a 36-minute pummelling.
Siniakova may not have been quite herself as she appeared to struggle with an abdomen injury but Saville was merciless, attacking with venom and dropping just nine points in a 23-minute opening set.
Siniakova called for the trainer at the end of the first set but after losing the first game and serving a double fault at the start of her opening service game in the second, she decided to retire.
It means Melbourne's Saville has now, remarkably, made the fourth round in two successive WTA 1000 events, the biggest women's tournaments outside the grand slams, in both Indian Wells and Miami as her striking revival continues.
Less than six weeks ago, Saville was ranked 627 in the world as she trod nervously on the comeback trail after having endured 10 months out of the game following Achilles surgery to cure a chronic long-standing problem.
Now, if she can win her eminently winnable last-16 match against either lucky loser Lucia Bronzetti or qualifier Anna Kalinskaya, Saville will be up to at least No.127 when the next rankings come out on April 4 - a potential rise of 500 places in a month-and-a-half.
With the help of a few technical changes to the way she holds her racquet and still having to be careful about managing her repaired Achilles, Saville has excelled on her first competitive trip outside Australia for two-and-a-half years.
First, she reached the quarter-finals in Guadalajara, followed by making it through qualifiers in Indian Wells to the fourth round and now taking full advantage of a Miami wildcard as she currently sits at No.249 in the rankings.
Saville - formerly Daria Gavrilova before getting married to fellow Australian player Luke Saville in December - is the second wildcard in two years to reach Miami's last 16, following Ana Konjuh in the 2021 event.
The Russian-born player may still be a long way from getting back to the heady days five years ago when she reached the world's top 20 but Saville is enjoying every minute of her comeback.
She told the WTA website recently how she felt "this is cool, I love just being at tournaments again".