Premier League side Spurs will play their fourth Europa League fixture of the season on Thursday without a string of first-team players after attackers Timo Werner (groin) and Mikey Moore (illness) joined an already hefty list of absentees.
It makes an already tricky fixture in Turkey even tougher but Australian boss Postecoglou is excited to see how his players fare in front of Galatasaray's ferocious support, which memorably welcomed Manchester United in 1993 with a 'Welcome to Hell' sign.
"I'm sure that they're all looking forward to it. That's why you play football," Postecoglou said.
"We're looking forward to it. It's a fantastic stadium, the supporters create an unbelievable atmosphere here, they love the big European nights.
"They're a very, very good team. It's exactly the kind of game you want to be involved in in Europe, whether you're young, you're old, irrespective of the role you have, you look forward to it.
"Galatasaray at their home stadium, with the fans behind them, there is a great energy in all their games so it's a great test for us and one we're looking forward to."
Spurs have won nine of their last 11 matches in all competitions, which includes three victories in the Europa League, despite Postecoglou shuffling his pack for each group fixture.
And the 59-year-old plans to do the same again in Istanbul.
"Through the Europa league we've rotated the team," Postecoglou explained.
"We'll make changes tomorrow night but again it's about making sure we have a team out there we believe can match the opposition and get a result for us."
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