Melbourne will be sweating on Brandon Smith passing a fitness test on his injured hand with their hooking stocks hitting a new low with Tyran Wishart also ruled out of Saturday's NRL game against Parramatta.
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Harry Grant, their best player in their one-point win over South Sydney last round, was ruled out on Tuesday after contracting COVID-19 and his housemate Wishart will now also miss the AAMI Park match.
Wishart, who made his NRL debut at hooker in round one, hasn't tested positive but has been deemed a household contact of Grant.
The pair will have to isolate for seven days and are expected to be available for round four.
Smith was named among the extended reserves after undergoing surgery on his hand which he broke early in their round one match.
While the 25-year-old is confident he will be able to take on the Eels, Storm football manager Frank Ponissi was more circumspect.
"He's probably unlikely to play - it might just fall a couple of days short," Ponissi said.
"He's come along really well and the surgeon is really happy but he's just got to get strength back in his hand.
"We named him as an outside chance ... he's in the mix and we will see how he goes."
The replacements for Grant and Wishart in the squad of 24 to face the Eels will be named later in the week.