Emily Pedersen and Maja Stark were Europe's only winners on Friday morning as they beat Ally Ewing and Jennifer Kupcho, although the American pair fought back from four down after five holes to take the match all the way to the 18th.
World No.1 Nelly Korda, who has yet to taste victory in the biennial contest, led from the front as she partnered Allisen Corpuz to a 3&2 victory over England's Charley Hull and German rookie Esther Henseleit.
Korda and Corpuz also won both of their foursomes matches in Spain last year and became the first American pair to win three in a row in the alternate shot format by winning the 14th, 15th and 16th.
Rose Zhang and Lauren Coughlin then completed a 3&2 win over Swiss rookie Albane Valenzuela and France's Celine Boutier, before world No.2 Lilia Vu and rookie Sarah Schmelzel defeated Linn Grant and Carlota Ciganda by the same margin to make it 3-0 to the home side.
A second successive 4-0 whitewash in the opening session always looked unlikely as Pedersen and Stark took command of match three in the early stages, but Europe captain Suzann Pettersen will have breathed a massive sigh of relief to see the Scandinavian pair get over the line.
Tournament organisers had earlier been forced to apologise for major issues getting spectators into the golf course which meant the first tee grandstands were nowhere near full as play got under way.
Fans posted footage of long lines waiting for shuttle buses on social media, with some reports of people simply giving up and going home.
"We recognise and deeply apologise to all fans affected by the challenges with shuttling from parking to the golf course," the LPGA said in a statement.
"We've made significant changes to our transportation system to mitigate these issues moving forward, and we're working on ways to express our regret to those impacted."