A new era begins for Italian rugby after the Argentine took over from Kieran Crowley, who led Italy in the last two Six Nations championships and the World Cup, and Quesada has named five uncapped players in the 34-man party.
Menoncello became the youngest Six Nations try scorer on his debut against France in 2022, but missed the World Cup after picking up a bicep injury in a warm-up game.
Italy begin their Six Nations campaign in Rome against England on February 3.
Italy squad:
Forwards: Pietro Ceccarelli, Danilo Fischetti, Matteo Nocera, Luca Rizzoli, Mirco Spagnolo, Giosue Zilocchi, Gianmarco Lucchesi, Marco Manfredi, Giacomo Nicotera, Niccolo Cannone, Edoardo Iachizzi, Federico Ruzza, Andrea Zambonin, Lorenzo Cannone, Riccardo Favretto, Alessandro Izekor, Michele Lamaro, Sebastian Negri, Ross Vintcent, Manuel Zuliani
Backs: Alessandro Garbisi, Martin Page-Relo, Stephen Varney, Tommaso Allan, Paolo Garbisi, Juan Ignacio Brex, Tommaso Menoncello, Federico Mori, Marco Zanon, Pierre Bruno, Ange Capuozzo, Monty Ioane, Simone Gesi, Lorenzo Pani
26°C