The film, directed by Kevin McDonald, features footage from the two One to One benefit concerts that John Lennon, Yoko Ono and Elephant's Memory performed at Madison Square Garden in August 1972.
These concerts were the only full live shows Lennon did between the breakup of the Beatles and his death in 1980.
Ono Lennon insists the documentary is about more than music.
"Some people might be imagining, that it would just be a concert film," he told Variety.
"But really the concert is a window through which you can view the lives of my parents at that time, moving to New York from the UK, and then through their eyes, you view the greater political and cultural landscape of the early '70s.
"It's very multi-layered and has macro and micro narratives that are all equally compelling in different ways."
Ono Lennon described his parents as the "first reality TV couple" because they recorded so much of their private lives.
"I think it's really interesting that John and Yoko famously recorded their lives all the time via video — I mean, via 16 millimetre film," he said.
They were documenting their lives daily when they were living in England from 1969 to 1971.
When they moved to New York, they recorded their own phone calls, because the FBI had been monitoring them and (US President Richard) "Nixon was trying to deport my dad".
"They were doing that in the early '70s, before reality television and before social media and before memes — they were already kind of ahead of their time in that regard," he said.
"As far as I am concerned, it's like they were the first reality TV celebrity couple."
He also credited them as being the first to use memes to spread their ideas, such as "Give peace a chance" or "War is over if you want it" or "Hair Peace".
"They're arguably kind of mimetic campaigns for social issues," he said.
"So it's fascinating to see how they were able to use the technology to document and record their private lives while also sort of using that level of intimacy to create media that was important to them.
"They wanted to show who they were and the truth of who they were, and they wanted people to see them unmanicured and unfiltered - and I feel like no one was really doing that at the time," he said.