The 50-year-old supermodel became part of the "heroin chic" fashion trend in the mid 1990s with her "waif"-like style and Moss has now confessed she was singled out for criticism because she was different to previous stars of the catwalk.
Speaking in new Disney Plus documentary In Vogue: The 90s, Moss explained: "Parents would come up to me and say, 'My daughter's anorexic'. It was awful.
"I think because I was just skinny, and people weren't used to seeing skinny. But if I'd been more buxom, it wouldn't have been such a big deal. It's just that my body shape was different from the models before me."
Moss was just a teenager when she shot to fame as a model and one of her most famous shoots for Vogue magazine - which she posed in lingerie - helped cement her as part of the trend, but the pictures shot by photographer Corinne Day sparked a major backlash.
Vogue fashion editor Catherine Kasterine said of the shoot: "The public were not ready. They were absolutely appalled. Immediately, the pictures were completely vilified and slammed. Perhaps we'd underestimated how that look had in our minds been quite normal."
Vogue editor Dame Anna Wintour added: "That look – very undernourished-looking model – made people uncomfortable.
"Many of us at Vogue worried about heroin chic or anorexia, all the things that are associated with that look. It got to such a fever pitch. I remember physically being in the White House when the Clinton administration took the issue on."
In the documentary, Moss also opened up about her controversial 1990s advertising campaign for Calvin Klein in which she posed topless with Mark Wahlberg during his years in the music industry as Marky Mark.
She said: "It was quite overwhelming. I was 18, you know, he was a big superstar rapper, and I still felt like I was just a girl from Croydon. They asked me to be topless. It was just a lot of people on set, a lot of men. I did feel vulnerable."
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