The Skyfall singer opened her delayed Weekends With Adele concert series at The Colosseum at Caesars Palace in November 2022 and while she has extended the dates several times since then, she's now confirmed she won't be doing so after her final shows later in November.
"This really is the beginning of the end. There are no other f****** shows," The Sun on Sunday newspaper's Bizarre column reported she told the crowd on Friday.
"I'm not going to be like, 'surprise'. This is the end.
"It's (the 100th and final show) the weekend before Thanksgiving, isn't it?
"And that's the last one. I don't have any plans to be on stage indefinitely, really."
Adele, mother to 11-year-old son Angelo with ex-husband Simon Konecki, is in a relationship with sports agent Rich Paul.
She admitted her life was a "thousand times better" since her residency started and she was "genuinely sad" for it to come to an end.
"They say that if you want things and you are looking for things in life, you have to pay the universe and then it pays you back tenfold," she said.
"I feel like that's what's happened with this show for me.
"My life is a thousand times better.
"My life, not my career, not my music - I'm talking about my actual life.
"And I really, truly think that this show has been my best friend throughout all of that and I'm so genuinely sad."
The 36-year-old star has vowed to take a lengthy break when her Las Vegas commitments end.
"I have spent the last seven years building a new life for myself, and I want to live it," she told the audience at the final show of her 10-night residency in Munich, Germany, in August.
"I want to live the new life that I have been building."
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