The owner of the Premier League club Vichai Srivaddhanaprabha, fellow passengers Nusara Suknamai and Kaveporn Punpare, and pilot Eric Swaffer and his partner Izabela Roza Lechowicz, also a professional pilot, were killed in the crash on October 27, 2018.
No one travelling in the helicopter survived after it hit the ground and burst into flames next to the King Power Stadium.
The jury inquest, which will begin at Leicester Coroners' Court sitting at Leicester City Hall, is expected to hear tributes to each of the victims on Monday.
In a statement released through lawyers representing the victims' families, Srivaddhanaprabha's son Aiyawatt, who succeeded his father as chairman of Leicester City, said the family is looking forward to the hearing.
"My family embraces the inquest process and look forward to the explanation into how and why my father lost his life, and what has been done to ensure that other families will not suffer the same terrible pain of loss that has been inflicted on us," he said.
Izabela Lechowicz's sister Kate said there were still many questions to be answered about the crash.
"Waiting for the inquest has been tormenting, leaving many unanswered questions and frustrations lingering for over six years since the tragic loss of our Eric and Izabela," she said.
It comes just days after Srivaddhanaprabha's family's legal representatives said a STG2.15 billion ($A4.27 billion) legal claim has been launched over the crash.
Srivaddhanaprabha's family allege Leonardo S.p.A., which manufactured the helicopter, is liable for his death.
An investigation found the crash happened after the pilot's pedals became disconnected from the tail rotor, and the helicopter plummeted 130 metres to the ground before it was rapidly engulfed in fire.
The inquest, expected to last three weeks, will examine the mechanical cause of the crash.