Maxwell and Zampa will be making their first appearance since Australia's World Cup final triumph over India, joining young Tanveer Sangha in a three-pronged spin attack on a Greenfield International Stadium expected to turn on Sunday (Monday morning AEDST).
The duo will replace seamer Jason Behrendorff and allrounder Aaron Hardie.
Australia trail the five-match series 1-0 after India were able to lick their wounds from their World Cup heartbreak and win Friday's series opener in a last-ball, high-scoring thriller at Visakhapatnam.
The home side has selected an unchanged XI.
Australia: Matthew Wade (capt), Steve Smith, Matthew Short, Josh Inglis, Glenn Maxwell, Marcus Stoinis, Tim David, Sean Abbott, Nathan Ellis, Adam Zampa, Tanveer Sangha.
India: Suryakumar Yadav (capt), Yashasvi Jaiswal, Ruturaj Gaikwad, Ishan Kishan, Tilak Varma, Rinku Singh, Axar Patel, Ravi Bishnoi, Arshdeep Singh, Mukesh Kumar, Prasidh Krishna.
