In the wheat belt town of Forbes in the state's central west, some 600 people have been told to evacuate their homes by 4pm Thursday as rising waters threaten to cut off properties and strand residents.
Cattle farmer Charles Laverty was busy sandbagging his property on the outskirts of Forbes with about a third of his paddocks already underwater on Thursday.
Continued flooding has hit inland communities hard, as farmers struggle to recover from repeated bouts of destruction to crops and livestock.
"A lot of (my neighbours) have given up on harvesting those areas, which is very expensive," Mr Laverty told AAP.
"The losses are going to be devastating for them."
Despite warnings from authorities the Lachlan River would reach 1952 levels on Friday, locals remained unsure how the peaks would hit the landscape due to significant changes in infrastructure.
"No one really knows what's going to happen," Mr Laverty said.
Some residents in the evacuation zone in Forbes opted to stay in their homes despite urgent warnings from the NSW SES, telling residents in low-lying parts of Forbes to leave before nightfall.
Some locals made other preparations, including sourcing generators and bottled water in case they lost access to power and plumbing, Gavin Tom, vice-chairman of the Parkes-Forbes NSW Farmers Association told AAP.
"The problem isn't so much whether the house gets inundated - it's more if the services get affected by the floods," he said.
Record flooding is forecast in Forbes on Friday night when the Lachlan River is expected to peak, NSW SES Zone Commander Ben Pickup said.
He said peaks would continue through to Saturday morning.
"I really encourage the community of Forbes - please listen to the warning information," he said.
"Please, please follow that messaging."
Emergency Services Minister Steph Cooke said she understood the exhaustion felt by communities across central and southern NSW, but warned flooding would continue across inland catchments in coming days.
"Everyone is flood weary but we need to keep working through this. We need to keep working together," she told reporters on Thursday.
"Whilst we are starting to see blue skies emerge ... the flooding risk is very, very high at the moment.
"We are continuing to see peaks roll through the system even though there isn't water falling from the sky at the moment."
Major flooding on the Lachlan River on Thursday is causing inundations in the town of Nanami, and major flooding continues further downstream at Condobolin, with the river not expected to fall for weeks.
The Murrumbidgee River has also burst its banks, with major floods peaking at Gundagai on Wednesday night, and major peaks possible at Wagga Wagga on Thursday night.
Ms Cooke expressed her sympathies for the Gunnedah community, which has been hit by seven floods in recent weeks, and Wagga Wagga, which faces its fourth inundation since August.
Renewed, moderate flooding is also occurring at Albury and Corowa on the Murray River after widespread falls.
Ongoing significant flooding is continuing in the border town of Moama, where water levels are likely to remain high through to next week.
The SES has received 431 calls for assistance and conducted 15 flood rescues in the past 24 hours.
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